Profile

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Krishna Kurthkoti, PhD

DBT Ramalingaswami Faculty Fellow

+91-471-2529 519

Kurthkoti@rgcb.res.in

KrishnaKurthkoti
KrishnaKurthkoti

Krishna Kurthkoti, PhD

DBT Ramalingaswami Faculty Fellow

+91-471-2529 519

Kurthkoti@rgcb.res.in

  • Profile

    • PhD Indian Institute of Science, Bangalore
    • M.Sc Bangalore University
    • B.Sc Bangalore University
    • 2017- present DBT Ramalingaswmi Faculty fellow, RGCB
    • 2016 (July)- 2017 (April) CSIR Pool Officer, Indian Institute of Science
    • 2012-2016 Postdoctoral Fellow, Rutgers University, New Jersey
    • 2011-2012 Postdoctoral Fellow, Sanford Burnham Medical Research Institute, San Diego
    • 2010-2011 Research Scholar Indian Institute of Science
    • 2003-2010 PhD, Department of Microbiology and Cell Biology, Indian Institute of Science
    • 2003 (April)- 2003 (June) Indian Academy of Sciences, Summer fellow, Indian Institute of Science
    • DBT Ramalingaswamy Fellowship (2016)
    • CSIR Senior Research fellowship (2005)
    • CSIR Junior Research Fellowship (2003)
    • Indian Academy of Sciences Summer research fellowship (2003)
  • Publications

    Publications

    1. Krishna Kurthkoti*, Hamel Amin*, Mohlopheni Marakalala, Saleena Ghanny, Selvakumar Subbian, Alexandra Sakatos, Jonathan Livny, Sarah Fortune, Michael Berney and G Marcela Rodriguez (2017). Mycobacterium tuberculosis' capacity to survive iron-starvation might enable it to persist in iron-deprived microenvironments of human granulomas mBio (article in press)* Equal contribution
    2. Xiao Peng Xiong, Krishna Kurthkoti, Kungyen Chang, Jian-Liang, Ren Xing Jie Nij Q Tariq Rana, Rui Zhou (2016).miR-34 Modulates Innate Immunity and Ecdysone Signalling in DrosophilaPLOSPathogens doi:10.1371/journal.ppat.1006034
    3. KurthkotiK,Priyanka Tare, Rakhi Paitchowdhury, Vykuntham Naga Gowthami, Maria J Garcia, Roberto Colangeli, Dipankar Chatterji, Valakunja Nagaraja, G Marcela Rodriguez.The mycobacterial iron‚Äźdependent regulator IdeR induces ferritin (bfrB) by alleviating Lsr2 repression(2015).MolecularMicrobiology 98 (5)864-877.
    4. Xiao-PengXiong,GeorgVogler,KrishnaKurthkoti,AnastasiaSamsonova,RuiZhou.SmD1modulatesthemiRNApathwayindependentlyofitspre-mRNAsplicingfunction(2015). PlosGeneticsdoi:10.1371/journal.pgen.1005475
    5. XiongXP,KurthkotiK,Chang KY,Lichinchi G,DeN,SchneemannA,MacraeIJ,RanaTM,PerrimonN,ZhouR.Core small nuclear ribonucleoprotein particle splicing factor SmD1 modulates RNA interference in Drosophila (2013). ProcNatlAcadSciUSA,110(41):16520-5
    6. RexK,KurthkotiK,VarshneyU. Hypersensitivity of hypoxia grown Mycobacterium smegmatis to DNA damaging agents: Implications of the DNA repair deficiencies in attenuation of mycobacteria.(2013).MechAgeingDev,134(10):516-22.
    7. ParikhA*,KumarD*,ChawlaY*,KurthkotiK,KhanS,VarshneyU,NandicooriVK.Development of a new generation of vectors for gene expression, gene replacement, and protein-protein interaction studies in mycobacteria(2013).ApplEnvironMicrobiol,79(5):1718-29. * Equal contribution
    8. KurthkotiK and UmeshVarshney.Distinct mechanisms of DNA repair in mycobacteria and their implications in attenuation of the pathogen growth.(2012).MechAgeingDev,133(4):138-46
    9. Kurthkoti K and Varshney U. Base excision and nucleotide excision repair pathways in mycobacteria (2011). Tuberculosis, 91(6): 533-43
    10. KurthkotiK and Varshney U.Detrimentaleffectsofhypoxiaspecificexpressionofuracil DNAglycosylase(Ung) in Mycobacterium smegmatis. (2010). JBacteriol,192,6439-46.
    11. Malshetty V,KurthkotiK,ChinaA,MallickB,YamunadeviS,SangPB,SrinivasanN,NagarajaVandVarshneyU.Novelinsertion and deletionmutants of RpoBwhichrender MycobacteriumsmegmatisRNApolymeraserecalcitranttorifampicinmediated inhibition of transcription(2010).Microbiology 156,1565-73.
    12. MalshettyVS,JainR,SrinathT,KurthkotiK and VarshneyU.Synergistic effects of UdgBandUnginmutation prevention and protection against commonly encountered DNA damaging agents in Mycobacteriumsmegmatis(2010).Microbiology 156,940-949.
    13. KurthkotiK,Srinath.T,KumarP.,MalshettyVS,SangPB,JainR,ManjunathRand VarshneyU. A distinct physiological role of MutY in mutation prevention in mycobacteria(2010).Microbiology,156,88-93.
    14. KurthkotiK ,KumarP,JainR.andVarshneyU.Important role of the nucleotide excision repair pathway in Mycobacterium smegmatis in conferrin gprotection against commonly encountered DNA-damaging agents (2008). Microbiology 154,2776-2785.
    15. KumarP,KrishnaK,SrinivasanR,Ajitkumar P and Varshney U.Mycobacterium tuberculosis and Escherichiacoli nucleoside diphosphate kinases lack multifunctional activities to process uracil containing DNA(2004).DNA Repair 3,1483-1492.
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  • Alumni