Chronic Disease Biology

Chronic Disease is a long-lasting condition that can be controlled but not cured. Chronic diseases are the leading causes of death and disability worldwide. Disease rates from these conditions are accelerating globally, advancing across every region and pervading all socioeconomic classes. The World Health Organization estimates that the major chronic diseases currently account for almost 60% of all deaths and 43% of the global burden of disease. By 2020 their contribution is expected to rise to 73% of all deaths and 60% of the global burden of disease. Moreover, 79% of the deaths attributed to these diseases occur in the developing countries. Four of the most prominent chronic diseases - cardiovascular diseases (CVD), cancer, chronic obstructive pulmonary disease and type 2 diabetes - are linked by common and preventable biological risk factors, notably high blood pressure, high blood cholesterol and overweight, and by related major behavioral risk factors: unhealthy diet, physical inactivity and tobacco use. RGCB's chronic disease biology research has two major components - Cancer Research Program and Cardiovascular & Diabetes Research Program