Roshna Lawrence Gomez, PhD Student
Gene regulation in M. tuberculosis under stress
To survive in stressful environments microorganisms must make appropriate adaptive responses which are reflected by changes in its transcriptional machinery. During infection, and intracellular residency, M. tuberculosis is exposed to different stress conditions as part of the host defence mechanisms that try to eliminate the bacterium. My work aims at the structural and functional characterization of a mycobacterial stress associated transcription factor that seems to play a role in the survival of the bacterium during dormancy.