Autoimmune Regulator (AIRE) - Takes a Hypoxia inducing factor 1A (HIF1A) route to regulate FOXP3 expression in PCOS

Renjini Ambika Padmanabhan, Betcy Susan Johnson, Ajay Kumar Dhyani, Sathy M Pillai, K Jayakrishnan, Malini Laloraya (2022)
American Journal of Reproductive Immunology     https://doi.org/10.1111/aji.13637

Son of sevenless 1 (SOS1), the RasGEF, interacts with ER&lpha; and STAT3 during embryo implantation

Renjini A Padmanabhan, Damodaranpillai P Zyju, Anand G Subramaniam, Jaya Nautiyal, Malini Laloraya (2022)
Journal of Molecular Endocrinology     https://doi.org/10.1530/jme-22-0089

Polycystic ovary syndrome and immune deregulation: what do hormones want to say?

Betcy Susan Johnson, Malini Laloraya (2022)
Exploration of Immunology     https://doi.org/10.37349/ei.2022.00058

Derailed peripheral circadian genes in polycystic ovary syndrome patients alters peripheral conversion of androgens synthesis.

Betcy Susan Johnson, Meera B Krishna, Renjini A Padmanabhan, Sathy M Pillai, K Jayakrishnan, Malini Laloraya (2022)
Human Reproduction     https://doi.org/10.1093/humrep/deac139

Semen Proteomics of COVID-19 Convalescent Men Reveals Disruption of Key Biological Pathways Relevant to Male Reproductive Function.

Ghosh S, Parikh S, Nissa MU, Acharjee A, Singh A, Patwa D, Makwana P, Athalye A, Barpanda A, Laloraya M, Srivastava S, Parikh F (2022)
ACS Omega     doi.org/10.1021/acsomega.1c06551

Vanadium pentoxide nanoparticle mediated perturbations in cellular redox balance and the paradigm of autophagy to apoptosis.

Suma PR, Padmanabhan RA, Telukutla SR, Ravindran R, Velikkakath AKG, Dekiwadia CD, Paul W, Laloraya M, Srinivasula SM, Bhosale SV, Jayasree RS. (2020)
Free Radical Biology and Medicine     161:198-211. doi: 10.1016/j.freeradbiomed.2020.10.008. Online ahead of print. PMID: 33065180 (IF- 6.17)

Transcriptional Regulation of Nos2 via STAT5B Binding to Nos2 Gene Promoter Mediates Nitric Oxide Production: Relevance in β-Cell Maintenance.

Joseph A, Nair LCR, Johnson BS, Thomas PL, Padmanabhan RA, Puthumadathil N, Laloraya M. (2019)
Cellular Physiology and Biochemistry     52(1):141-155. doi: 10.33594/000000010. Epub 2019 Feb 18. (IF- 5.500)

Silencing of dedicator of cytokinesis (DOCK180) obliterates pregnancy by interfering with decidualization due to blockage of nuclear entry of autoimmune regulator (AIRE).

Mohan JJ, Narayan P, Padmanabhan RA, Joseph S, Kumar PG, Laloraya M. (2018)
American Journal of Reproductive Immunology     80(1), 1-14. doi: 10.1111/aji.12844. [Epub ahead of print] (IF- 2.745)

Impaired Arginine Metabolism Coupled to a Defective Redox Conduit Contributes to Low Plasma Nitric Oxide in Polycystic Ovary Syndrome.

Krishna MB, Joseph A, Thomas PL, Dsilva B, Pillai SM, Laloraya M. (2017)
Cellular Physiology and Biochemistry     43(5):1880-1892. doi: 10.1159/000484107. Epub 2017 Oct 20.

Murine uterine decidualization is a novel function of autoimmune regulator-beyond immune tolerance.

Soumya V, Padmanabhan RA, Titus S, Laloraya M. (2016)
American Journal of Reproductive Immunology     76(3):224-34. doi: 10.1111/aji.12538. Epub 2016 Jul 19.

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