Rajiv Gandhi Centre for Biotechnology (RGCB), Department of Biotechnology, Government of India

Star-PAP controls oncogene expression through primary miRNA 3'-end formation to regulate cellular proliferation and tumour formation.

Mohanan, N. K., Shaji, F., Sudheesh, A. P., Arathi, B. P., Sundaresan, N. R., & Laishram R. S. (2024)

Biochimica et biophysica acta. Molecular basis of disease 167080. Advance online publication. https://doi.org/10.1016/j.bbadis.2024.167080

Proto-oncogene cSrc-mediated RBM10 phosphorylation arbitrates anti-hypertrophy gene program in the heart and controls cardiac hypertrophy

Feba Shaji, Neeraja K Mohanan, Sumayya Shahzad, Gowri V P, Arathi Bangalore Prabhashankar, Nagalingam R Sundaresan, Rakesh S Laishram (2024)

Life Sciences doi.org/10.1016/j.lfs.2024.122482

Tyrosine phosphorylation controlled poly(A) polymerase I activity regulates general stress response in bacteria

Nimmy Francis, Malaya R Behera, Kathiresan Natarajan, Rakesh S Laishram (2022)

Life Science Alliance doi: 10.26508/lsa.202101148

Star-PAP RNA Binding Landscape Reveals Novel Role of Star-PAP in mRNA Metabolism That Requires RBM10-RNA Association

Ganesh R. Koshre, Feba Shaji ,Neeraja K. Mohanan, Nimmy Mohan,Jamshaid Ali and Rakesh S. Laishram (2021)

International Journal of Molecular Sciences doi.org/10.3390/ijms22189980

Transgenesis of mammalian PABP reveals mRNA polyadenylation as a general stress response mechanism in bacteria.

Francis N., Laishram R. S. (2021).

iScience 24(10), 103119. https://doi.org/10.1016/j.isci.2021.103119

Alternative polyadenylation: An enigma of transcript length variation in health and disease

Neeraja K Mohanan, Feba Shaji, Ganesh R Koshre, Rakesh S Laishram (2021)

Wiley Interdiscip Rev RNA doi: 10.1002/wrna.1692

Star-PAP controlled alternative polyadenylation coupled poly(A) tail length regulates expression in hypertrophic heart

Sudheesh, A.P., Mohan, N., Nimmy, F., Rakesh S. Laishram*, and Richard Anderson* (*Corresponding Author) (2019)

Nucleic Acid Res. gkz875 (https://doi.org/1 0.1093/nar/gkz875)

A splicing-independent function of RBM10 controls specific 3'UTR processing to regulate cardiac hypertrophy.

Mohan, N., Kumar, V., Kandala, D., Kartha, C.C., and Rakesh S. Laishram. (2018)

Cell Reports. doi.org/10.1016/j.celrep.2018.08.077

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Rakesh S . Laishram, PhD,FNASc

Scientist F
Swarna Jayanti Fellow

Selected Publications

Star-PAP controls oncogene expression through primary miRNA 3'-end formation to regulate cellular proliferation and tumour formation.

Proto-oncogene cSrc-mediated RBM10 phosphorylation arbitrates anti-hypertrophy gene program in the heart and controls cardiac hypertrophy

Tyrosine phosphorylation controlled poly(A) polymerase I activity regulates general stress response in bacteria

Star-PAP RNA Binding Landscape Reveals Novel Role of Star-PAP in mRNA Metabolism That Requires RBM10-RNA Association

Transgenesis of mammalian PABP reveals mRNA polyadenylation as a general stress response mechanism in bacteria.

Alternative polyadenylation: An enigma of transcript length variation in health and disease

Star-PAP controlled alternative polyadenylation coupled poly(A) tail length regulates expression in hypertrophic heart

A splicing-independent function of RBM10 controls specific 3'UTR processing to regulate cardiac hypertrophy.

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Rakesh S . Laishram, PhD,FNASc

Scientist F Swarna Jayanti Fellow

Selected Publications

Star-PAP controls oncogene expression through primary miRNA 3'-end formation to regulate cellular proliferation and tumour formation.

Proto-oncogene cSrc-mediated RBM10 phosphorylation arbitrates anti-hypertrophy gene program in the heart and controls cardiac hypertrophy

Tyrosine phosphorylation controlled poly(A) polymerase I activity regulates general stress response in bacteria

Star-PAP RNA Binding Landscape Reveals Novel Role of Star-PAP in mRNA Metabolism That Requires RBM10-RNA Association

Transgenesis of mammalian PABP reveals mRNA polyadenylation as a general stress response mechanism in bacteria.

Alternative polyadenylation: An enigma of transcript length variation in health and disease

Star-PAP controlled alternative polyadenylation coupled poly(A) tail length regulates expression in hypertrophic heart

A splicing-independent function of RBM10 controls specific 3'UTR processing to regulate cardiac hypertrophy.

Scientist F
Swarna Jayanti Fellow