Scientist E-II
Rajiv Gandhi Centre for Biotechnology
The primary focus of my lab is on deciphering the signaling pathways initiated in tumor microenvironment for the induction and maintenance of self-renewal ability in cancer stem cells. In parallel, we exploit the use of peptides in cancer biology for various purposes. Recently we identified the significance of a host defense peptide in inducing apoptosis in cancer cells. Understanding the molecular mechanism of this process revealed the possible exploitation of the immunomodulatory pathways by host defense peptides in inducing cell death in cancer cells. This property offers a therapeutic potential to this peptide in cancer therapy, specifically for cancer types that are resistant to conventional therapies.
Rajiv Gandhi Centre for Biotechnology
Rajiv Gandhi Centre For Biotechnology
Rajiv Gandhi Centre For Biotechnology
Rajiv Gandhi Centre For Biotechnology
National Centre for Biological Sciences, Bangalore
National Centre for Biological Sciences, Bangalore
National Centre for Biological Sciences, Bangalore
Regional Cancer Centre, Thiruvananthapuram
Rajiv Gandhi Centre for Biotechnology
Cochin University of Science and Technology
"Apoptosis Inducing Peptide (SSTP1)": 202041016382 provisional patent, India.
"Apoptosis Inducing Peptide (SSTP1)"; PCT/IN2021/050371), USA
Member of Editorial board, Scientific Reports
Indian Association of Cancer Research (lLife member)
Kerala Academy of Sciences (Life member)