Scientist G
Rajiv Gandhi Centre for Biotechnology
The laboratory identifies natural products having chemotherapeutic, chemosensitizing and chemopreventive potential (specifically curcumin, resveratrol, tryptanthrin and uttroside B) explores their mechanism of action and validates them through pre-clinical models.
Rajiv Gandhi Centre for Biotechnology
Rajiv Gandhi Centre for Biotechnology
Rajiv Gandhi Centre for Biotechnology
Rajiv Gandhi Centre for Biotechnology
Dept. of Bioimmunotherapy, M.D. Anderson Cancer Center, Houston, Texas, USA
Rajiv Gandhi Centre for Biotechnology
Amala Cancer Research Centre, Thrissur
Govt. Training College, Thrissur
Govt College, Madappally
Fellow, National Academy of Sciences, Allahabad
Fellow, Academy of Sciences, Thiruvananthapuram, India
Ruby John Anto, A chemotherapeutic composition used in the treatment of cancer: Filing Number: #1184/Del/2004. IPR- Patent number: 241416, Date of grant-02/07/2010: Funding by DBT, Govt. of India
Ruby John Anto and Lakshmi R Nath, Uttroside B and derivatives thereof as therapeutics for hepatocellular carcinoma, funding by Rajiv Gandhi Centre For Biotechnology.
National Patent Application No. 201641018401 dated 28th May 2016
International patent Application No. PCT/ IN20 17/050204 dated 27th May 2017
Current patent Status
India- Replied to FER on Dec 14,2020 (Application in Amended Examination)
Signed an MOU with Oklahoma Medical Research Foundation, USA for the clinical translation of Uttroside B in liver cancer patients on January 31, 2017.
Transferred the technology to the multi-national company, Q Biomed. And received the first milestone payment on June 15, 2017.
(https://adisinsight.springer.com/drugs/800048876);
https://qbiomed.com/index.php/pipeline/uttroside
Received Orphan Drug Designation to Uttroside B on January 27, 2021.
https://www.prnewswire.com/news-releases/q-biomeds-uttroside-b-receives-us-fda-orphan-drug-designation-in-the-treatment-of-liver-cancer-301215876.html
https://www.biospace.com/article/releases/q-biomed-s-uttroside-b-receives-u-s-fda-orphan-drug-designation-in-the-treatment-of-liver-cancer/
Ruby John Anto and Jayesh Antony, Extracts from a plant, processes for obtaining the extracts and fractions and applications thereof, Filed on: 20.09.2010, Patent Application No. 2743/CHE/2010: Funding by RGCB
C Mohandas, Bala Nambisan, Ruby John Anto, Vino T. Cheriyan and S. Nishanth Kumar. Anticancer activity of a cyclic dipeptide isolated from novel bacteria associated with Rhabditis sp., Filed on: 11-03-2011 Patent Application No. 820/CHE/2011). Funding by Indian Council for Agricultural Research
Member, European Association For Cancer Research
Member, American Association of Cancer Research
Member, Editorial board - PLOS ONE
Member, Editorial Board, Science Letters
Member, Editorial board- Asian Journal of Pharmacological Sciences
Member, American Society For Biochemistry And Molecular Biology
Member, The Biotech Research Society
Member, Board of Studies, M.Sc Chemistry, University of Kerala (2004-2007)
Member, Board of Studies, MSc Biotechnology, University of Calicut (2007-2010)