Selected Publications
Ponatinib and other clinically approved inhibitors of Src and Rho-A kinases abrogate dengue virus serotype 2- induced endothelial permeability.
Mishra SR, Modak A, Awasthi M, Sobha A, Sreekumar E (2025)
Virulence https:// doi: 10.1080/21505594.2025.2489751.
Host Factor Nucleophosmin 1 (NPM1/B23) Exerts Antiviral Effects against Chikungunya Virus by Its Interaction with Viral Nonstructural Protein 3.
Pradeep P, Sivakumar KC, Sreekumar E (2023)
Microbiology Spectrum https://doi.org/10.1128/spectrum.05371-22
Higher-temperature-adapted dengue virus serotype 2 strain exhibits enhanced virulence in AG129 mouse model.
Ayan Modak, Srishti Rajkumar Mishra, Mansi Awasthi, Sreeja Sreedevi, Archana Sobha, Arya Aravind, Krithiga Kuppusamy, Easwaran Sreekumar (2023)
FASEB J. https://doi.org/10.1096/fj.202300098R
Ethyl palmitate, an anti-chikungunya virus principle from Sauropus androgynus, a medicinal plant used to alleviate fever in ethnomedicine.
A Sagna, Reshma V R Nair, Neha Hulyalkar, S Rajasekharan, Vinodkumar T G Nair, K C Sivakumar, S R Suja, Sabulal Baby, Easwaran Sreekumar (2023)
Journal of Ethnopharmacology https://doi.org/10.1016/j.jep.2023.116366
Generation of a Live-Attenuated Strain of Chikungunya Virus from an Indian Isolate for Vaccine Development.
Sreeja R. Nair, Rachy Abraham, Easwaran Sreekumar (2022)
Vaccines 16 Nov 2022. doi.org/10.3390/vaccines10111939
Dengue virus or NS1 protein induces trans-endothelial cell permeability associated with VE-Cadherin and RhoA phosphorylation in HMEC-1 cells preventable by Angiopoietin-1.
Singh S, Anupriya MG, Modak A, Sreekumar E (2018)
Journal of General Virology 2018 Oct 24. doi: 10.1099/jgv.0.001163
Sphingolipid signaling modulates trans-endothelial cell permeability in dengue virus infected HMEC-1 cells.
M.G. Anupriya, Sneha Singha, Neha Vijay Hulyalkar, Easwaran Sreekumar (2018)
Prostaglandins & Other Lipid Mediators 136: 44-54
Preparation of Recombinant Alphaviruses for Functional Studies of ADP-Ribosylation. In: Chang P. (eds) ADP-ribosylation and NAD+ Utilizing Enzymes.
Abraham R., McPherson R.L., Sreekumar E., Leung A.K.L., Griffin D.E. (2018)
Methods in Molecular Biology vol 1813. Humana Press, New York, NY
Nucleophosmin (NPM1) / B23 in the proteome of human astrocytic cells restricts Chikungunya virus replication.
Rachy Abraham, Sneha Singh, Sreeja R Nair, Neha Vijay Hulyalkar, Arun Surendran, Abdul Jaleel, Easwaran Sreekumar* (2017)
Journal of Proteome Research 16:4144-4155
Interferon regulated gene (IRG) expression-1 signature in a mouse model of Chikungunya virus neurovirulence.
Sreeja R Nair, Rachy Abraham, Sankar Sundaram, Easwaran Sreekumar (2017).
Journal of NeuroVirology 23:886-902