Rajiv Gandhi Centre for Biotechnology (RGCB), Department of Biotechnology, Government of India

A Convolutional Neural Network- Based Deep Learning To Detect Reticulocytes From Human Peripheral Blood

Keerthy Reghunandanan, Lakshmi V.S, Rose Raj, Kasi Viswanath, Christeen Davis, Rajesh Chandramohanadas

Intelligence-Based Medicine doi.org/10.1016/j.ibmed.2024.100175

Search for novel Plasmodium falciparum PfATP4 inhibitors from the MMV Pandemic Response Box through a virtual screening approach

Keerthy Reghunandanan, Akhila T P, Nandini Krishnan, Darsana K M, Roshny Prasad, Shijulal Nelson-Sathi, Rajesh Chandramohanadas (2023)

Journal of Biomolecular Structure and Dynamics 10.1080/07391102.2023.2232459

Optical Diffraction Tomography and Image Reconstruction to measure host cell alterations caused by divergent Plasmodium species

Jessica Ong, Jeonghun Oh, Xiang Yong Ang, Renugah Naidu, Trang TT Chu, Jae Hyoung Im, Umar Manzoor, Tuyet Kha Nguyen, Seok-Won Na, Eun-Taek Han, Christeen Davis, Won Sun Park, Wanjoo Chun, Hojong Jun, Se Jin Lee, Sunghun Na, Jerry Chan, YongKeun Park, Bruce Russell, Rajesh Chandramohanadas*, Jin-Hee Han.(2022)

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 22 October 2022, 122026https://doi.org/10.1016/j.saa.2022.122026.

Chemically induced phenotypes during Blood stage Development of Plasmodium falciparum as indicators of drug mode of action

Reghunandanan K and Chandramohanadas R* (2022)

Frontiers in Drug Discovery. 12 October 2022. https://doi.org/10.3389/fddsv.2022.920850.

CD98 is a Plasmodium vivax receptor for human reticulocytes.

Malleret B, Abbas EH, Howland SW, Suwanarusk R, Ong, AS, Kosaisavee V, Chu TT., Sinha A, Gruszczyk J, Colin Y, Bertrand O, Lescar J, Maurer-Stroh S, Snounou G, Tham WH, Chandramohanadas R, Nosten F, Russell BM and Rénia L. (2021)

Nature Microbiology 2021 Aug;6(8):991-999

Comparing infrared spectroscopic methods for the characterization of Plasmodium falciparum-infected human erythrocytes.

Banas AM, Banas K, Chu TT, Naidu R, Hutchinson PE, Agrawal R, Lo M, Kansiz M, Roy A, Chandramohanadas R^* & Breese M. (2021)

Communications Chemistry (Nature Portfolio Journal) 4, Article number: 129 (2021)

A Deep Learning Approach to the Diagnosis of Malaria Infection: Automated and Rapid Cell Counting, Object Detection and Instance Segmentation using Mask-RCNN.

Loh DR, Yong WX, Yapeter J, Karupppasamy S and Chandramohanadas R^*. (2021)

Computerized Medical Imaging and Graphics 2021 Mar;88:101845.

Whole Cell Phenotypic Screening Of MMV Pathogen Box identifies Specific Inhibitors of Plasmodium falciparum merozoite maturation and egress.

Patra A, Hingamire T, Belekar M, Xiong A, Subramanian G, Bozdech Z, Preiser P, Shanmugam D and Chandramohanadas R^*. (2020)

Antimicrobial Agents & Chemotherapy 2020 Apr 21;64(5). pii: e01802-19.

Quantitative Mass Spectrometry of Human Reticulocytes Reveal Proteome-wide Modifications During Maturation.

Chu TT, Sinha A, Malleret B, Suwanarusk B, Park EJ, Naidu R, Das R, Dutta B, Ong ST, Verma NK, Chan JK, Nosten F, Rénia L, Sze SK, Russell B & Chandramohanadas R^*. (2018)

British Journal of Haematology 180(1): 118-133.

Targeted phenotypic screening in Plasmodium falciparum and Toxoplasma gondii reveals novel modes of action for MMV Malaria Box molecules.

Subramanian S, Belekar MA, Shukla A Tong JX, Sinha A, Chu TT, Kulkarni AS, Preiser PR, Reddy DS, Tan KSW, Shanmugam D and Chandramohanadas R^*. (2018)

mSphere 2018 Jan 17;3(1). pii: e00534-17.

^* Corresponding Author

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Rajesh Chandramohanadas, PhD

Scientist E-II

Selected Publications