Research Summary

Vaccines are one of the most powerful tools for preventing infectious diseases as well as the safest way to limit the effects of pandemic and epidemic risks on public health. The covid pandemic has been a huge inflexion point in vaccine innovation and has facilitated the development of numerous vaccine technologies to mitigate public health crises. Among other technologies, nucleic acid vaccines have emerged as a rapid and versatile platform for an emergency. The pandemic also highlights the need for the importance of viral genome surveillance to tackle viral variants, expand the number of antigens, and assess diverse delivery systems for vaccines against emerging viruses. In this context of viral vaccines, the laboratory is interested in 3 major interconnected streams,
Stream 1: Genomic surveillance of emerging/re-emerging viral threats using NGS approaches and integrating genetic diversity to design innovative vaccine antigen libraries.
Stream 2: Utilizing nucleic acids in viral vaccine development
Stream 3: Investigating human immune responses to vaccines and natural infections using systems immunology