Publication - 2021

Publication - 2021

• Basu P, Malvi SG, Joshi S, Bhatla N, Muwonge R, Lucas E, Verma Y, Esmy PO, Poli URR, Shah A, Zomawia E, Pimple S, Jayant K, Hingmire S, Chiwate A, Divate U, Vashist S, Mishra G, Jadhav R, Siddiqi M, Sankaran S, Prabhu PR, Kannan TPRA, Varghese R, Shastri SS, Anantharaman D, Gheit T, Tommasino M, Sauvaget C, Pillai MR, Sankaranarayanan R. Vaccine efficacy against persistent human papillomavirus (HPV) 16/18 infection at 10 years after one, two, and three doses of quadrivalent HPV vaccine in girls in India: a multicentre, prospective, cohort study. Lancet Oncol. 2021 Nov;22(11):1518-1529. doi: 10.1016/S1470-2045(21)00453-8. Epub 2021 Oct 8. Erratum in: Lancet Oncol. 2022 Jan;23(1):e16. PMID: 34634254; PMCID: PMC8560643.
• Scott AJ, Niitsu A, Kratochvil HT, Lang EJM, Sengel JT, Dawson WM, Mahendran KR, Mravic M, Thomson AR, Brady RL, Liu L, Mulholland AJ, Bayley H, DeGrado WF, Wallace MI, Woolfson DN. Constructing ion channels from water-soluble α-helical barrels. Nat Chem. 2021 Jul;13(7):643-650. doi: 10.1038/s41557-021-00688-0. Epub 2021 May 10. PMID: 33972753; PMCID: PMC7611114.
• Kumar R, Hortobagy GN, Albanell J, Arribas J, Norton L. In Memoriam: José Baselga's Journey in Cancer Medicine. Clin Cancer Res. 2021 Jun 15;27(12):3499-3502. doi: 10.1158/1078-0432.CCR-21-1624. PMID: 34117028.
• Mohanan NK, Shaji F, Koshre GR, Laishram RS. Alternative polyadenylation: An enigma of transcript length variation in health and disease. Wiley Interdiscip Rev RNA. 2021 Sep 27:e1692. doi: 10.1002/wrna.1692. Epub ahead of print. PMID: 34581021.
• Sandiford OA, Donnelly RJ, El-Far MH, Burgmeyer LM, Sinha G, Pamarthi SH, Sherman LS, Ferrer AI, DeVore DE, Patel SA, Naaldijk Y, Alonso S, Barak P, Bryan M, Ponzio NM, Narayanan R, Etchegaray JP, Kumar R, Rameshwar P. Mesenchymal Stem Cell-Secreted Extracellular Vesicles Instruct Stepwise Dedifferentiation of Breast Cancer Cells into Dormancy at the Bone Marrow Perivascular Region. Cancer Res. 2021 Mar 15;81(6):1567-1582. doi: 10.1158/0008-5472.CAN-20-2434. Epub 2021 Jan 26. PMID: 33500249.
• Reshmy R, Athiyaman Balakumaran P, Divakar K, Philip E, Madhavan A, Pugazhendhi A, Sirohi R, Binod P, Kumar Awasthi M, Sindhu R. Microbial valorization of lignin: Prospects and challenges. Bioresour Technol. 2022 Jan;344(Pt A):126240. doi: 10.1016/j.biortech.2021.126240. Epub 2021 Oct 28. PMID: 34737164.
• Reshmy R, Philip E, Madhavan A, Sirohi R, Pugazhendhi A, Binod P, Kumar Awasthi M, Vivek N, Kumar V, Sindhu R. Lignocellulose in future biorefineries: Strategies for cost-effective production of biomaterials and bioenergy. Bioresour Technol. 2022 Jan;344(Pt B):126241. doi: 10.1016/j.biortech.2021.126241. Epub 2021 Oct 28. PMID: 34756981.
• John S, K G G, Krishna AP, Mishra R. Neurotherapeutic implications of sense and respond strategies generated by astrocytes and astrocytic tumours to combat pH mechanical stress. Neuropathol Appl Neurobiol. 2021 Nov 23. doi: 10.1111/nan.12774. Epub ahead of print. PMID: 34811795.
• Sethumadhavan DV, Jabeena CA, Govindaraju G, Soman A, Rajavelu A. The severity of SARS-CoV-2 infection is dictated by host factors? Epigenetic perspectives. Curr Res Microb Sci. 2021 Dec;2:100079. doi: 10.1016/j.crmicr.2021.100079. Epub 2021 Oct 27. PMID: 34725650; PMCID: PMC8550886.
• Venugopal V, Sumi S. Molecular Biomarkers and Drug Targets in Brain Arteriovenous and Cavernous Malformations: Where Are We? Stroke. 2022 Jan;53(1):279-289. doi: 10.1161/STROKEAHA.121.035654. Epub 2021 Nov 17. PMID: 34784742.
• Govindaraju G, Chavali S, Rajavelu A. Plasmodium falciparum YTH2 Domain Binds to m6A-Containing mRNA and Regulates Translation. mBio. 2021 Dec 21;12(6):e0136721. doi: 10.1128/mBio.01367-21. Epub 2021 Nov 23. PMID: 34809465; PMCID: PMC8609348.
• Goyal R, Jerath G, Akhil R, Chandrasekharan A, Puppala ER, Ponneganti S, Sarma A, Naidu VGM, Santhoshkumar TR, Ramakrishnan V. Geometry encoded functional programming of tumor homing peptides for targeted drug delivery. J Control Release. 2021 May 10;333:16-27. doi: 10.1016/j.jconrel.2021.03.010. Epub 2021 Mar 13. PMID: 33722612.
• Gopalakrishnan S, Uma SK, Mohan G, Mohan A, Shanmugam G, Kumar VTV, J S, Chandrika SK, Vasudevan D, Nori SRC, Sathi SN, George S, Maliekal TT. SSTP1, a Host Defense Peptide, Exploits the Immunomodulatory IL6 Pathway to Induce Apoptosis in Cancer Cells. Front Immunol. 2021 Nov 19;12:740620. doi: 10.3389/fimmu.2021.740620. PMID: 34867962; PMCID: PMC8639500.
• Madhavan A, Arun KB, Binod P, Sirohi R, Tarafdar A, Reshmy R, Kumar Awasthi M, Sindhu R. Design of novel enzyme biocatalysts for industrial bioprocess: Harnessing the power of protein engineering, high throughput screening and synthetic biology. Bioresour Technol. 2021 Apr;325:124617. doi: 10.1016/j.biortech.2020.124617. Epub 2020 Dec 26. PMID: 33450638.
• Tarafdar A, Sirohi R, Gaur VK, Kumar S, Sharma P, Varjani S, Pandey HO, Sindhu R, Madhavan A, Rajasekharan R, Sim SJ. Engineering interventions in enzyme production: Lab to industrial scale. Bioresour Technol. 2021 Apr;326:124771. doi: 10.1016/j.biortech.2021.124771. Epub 2021 Jan 30. PMID: 33550211.
• Rajan A, Nadhan R, Latha NR, Krishnan N, Warrier AV, Srinivas P. Deregulated estrogen receptor signaling and DNA damage response in breast tumorigenesis. Biochim Biophys Acta Rev Cancer. 2021 Jan;1875(1):188482. doi: 10.1016/j.bbcan.2020.188482. Epub 2020 Nov 28. PMID: 33260050.
• Remya C, Dileep KV, Koti Reddy E, Mantosh K, Lakshmi K, Sarah Jacob R, Sajith AM, Jayadevi Variyar E, Anwar S, Zhang KYJ, Sadasivan C, Omkumar RV. Neuroprotective derivatives of tacrine that target NMDA receptor and acetyl cholinesterase - Design, synthesis and biological evaluation. Comput Struct Biotechnol J. 2021 Aug 3;19:4517-4537. doi: 10.1016/j.csbj.2021.07.041. PMID: 34471497; PMCID: PMC8379669.
• Mukesh RK, Kalam AA, Nag J, Jaikumar VS, Kunnakkadan U, Kumar NA, Suma SM, Rajavelu A, Johnson JB. Chandipura virus induces cell death in cancer cell lines of human origin and promotes tumor regression in vivo. Mol Ther Oncolytics. 2021 Oct 5;23:254-265. doi: 10.1016/j.omto.2021.09.009. PMID: 34761105; PMCID: PMC8554107.
• Gurevich DB, David DT, Sundararaman A, Patel J. Endothelial Heterogeneity in Development and Wound Healing. Cells. 2021 Sep 7;10(9):2338. doi: 10.3390/cells10092338. PMID: 34571987; PMCID: PMC8469713.
• Thankamony AP, Subbalakshmi AR, Jolly MK, Nair R. Lineage Plasticity in Cancer: The Tale of a Skin-Walker. Cancers (Basel). 2021 Jul 18;13(14):3602. doi: 10.3390/cancers13143602. PMID: 34298815; PMCID: PMC8306016.
• Chandran Latha K, Sreekumar A, Beena V, S S BR, Lakkappa RB, Kalyani R, Nair R, Kalpana SR, Kartha CC, Surendran S. Shear Stress Alterations Activate BMP4/pSMAD5 Signaling and Induce Endothelial Mesenchymal Transition in Varicose Veins. Cells. 2021 Dec 17;10(12):3563. doi: 10.3390/cells10123563. PMID: 34944071; PMCID: PMC8700678.
• Anandan V, Thulaseedharan T, Suresh Kumar A, Chandran Latha K, Revikumar A, Mullasari A, Kartha CC, Jaleel A, Ramachandran S. Cyclophilin A Impairs Efferocytosis and Accelerates Atherosclerosis by Overexpressing CD 47 and Down-Regulating Calreticulin. Cells. 2021 Dec 20;10(12):3598. doi: 10.3390/cells10123598. PMID: 34944106; PMCID: PMC8700718.
• Reshmy R, Philip E, Vaisakh PH, Raj S, Paul SA, Madhavan A, Sindhu R, Binod P, Sirohi R, Pugazhendhi A, Pandey A. Development of an eco-friendly biodegradable plastic from jack fruit peel cellulose with different plasticizers and Boswellia serrata as filler. Sci Total Environ. 2021 May 1;767:144285. doi: 10.1016/j.scitotenv.2020.144285. Epub 2021 Jan 4. PMID: 33429269.
• Mohan A, Raj R R, Mohan G, K P P, Thomas Maliekal T. Reporters of Cancer Stem Cells as a Tool for Drug Discovery. Front Oncol. 2021 Apr 22;11:669250. doi: 10.3389/fonc.2021.669250. PMID: 33968778; PMCID: PMC8100607.
• Unnikrishnan K, Thomas LV, Ram Kumar RM. Advancement of Scaffold-Based 3D Cellular Models in Cancer Tissue Engineering: An Update. Front Oncol. 2021 Oct 25;11:733652. doi: 10.3389/fonc.2021.733652. PMID: 34760696; PMCID: PMC8573168.
• Pradhan T, Kumar V, Surya H E, Krishna R, John S, Jissa VT, Anjana S, Chandramohan K, Nair SA. STIL Endows Oncogenic and Stem-Like Attributes to Colorectal Cancer Plausibly by Shh and Wnt Signaling. Front Oncol. 2021 Aug 12;11:581671. doi: 10.3389/fonc.2021.581671. PMID: 34485108; PMCID: PMC8416176.
• Haritha NH, Nawab A, Vijayakurup V, Anto NP, Liju VB, Alex VV, Amrutha AN, Aiswarya SU, Swetha M, Vinod BS, Sundaram S, Guijarro MV, Herlevich T, Krishna A, Nestory NK, Bava SV, Sadasivan C, Zajac-Kaye M, Anto RJ. Targeting Thymidylate Synthase Enhances the Chemosensitivity of Triple-Negative Breast Cancer Towards 5-FU-Based Combinatorial Therapy. Front Oncol. 2021 Jul 15;11:656804. doi: 10.3389/fonc.2021.656804. PMID: 34336653; PMCID: PMC8320437.
• Dharmapal D, Jyothy A, Mohan A, Balagopal PG, George NA, Sebastian P, Maliekal TT, Sengupta S. β-Tubulin Isotype, TUBB4B, Regulates The Maintenance of Cancer Stem Cells. Front Oncol. 2021 Dec 23;11:788024. doi: 10.3389/fonc.2021.788024. PMID: 35004310; PMCID: PMC8733585.
• Ramesh ST, Navyasree KV, Sah S, Ashok AB, Qathoon N, Mohanty S, Swain RK, Umasankar PK. BMP2K phosphorylates AP-2 and regulates clathrin-mediated endocytosis. Traffic. 2021 Nov;22(11):377-396. doi: 10.1111/tra.12814. Epub 2021 Sep 27. PMID: 34480404.
• Remadevi V, Muraleedharan P, Sreeja S. FOXO1: a pivotal pioneer factor in oral squamous cell carcinoma. Am J Cancer Res. 2021 Oct 15;11(10):4700-4710. PMID: 34765288; PMCID: PMC8569351.
• Azeez JM, Susmi TR, Remadevi V, Ravindran V, Sasikumar Sujatha A, Ayswarya RNS, Sreeja S. New insights into the functions of progesterone receptor (PR) isoforms and progesterone signaling. Am J Cancer Res. 2021 Nov 15;11(11):5214-5232. PMID: 34873457; PMCID: PMC8640821.
• Nayar S, Thangavel G. CsubMADS1, a lag phase transcription factor, controls development of polar eukaryotic microalga Coccomyxa subellipsoidea C-169. Plant J. 2021 Aug;107(4):1228-1242. doi: 10.1111/tpj.15380. Epub 2021 Jul 14. PMID: 34160095.
• Koshre GR, Shaji F, Mohanan NK, Mohan N, Ali J, Laishram RS. Star-PAP RNA Binding Landscape Reveals Novel Role of Star-PAP in mRNA Metabolism That Requires RBM10-RNA Association. Int J Mol Sci. 2021 Sep 15;22(18):9980. doi: 10.3390/ijms22189980. PMID: 34576144; PMCID: PMC8469156.
• Srinivas L, Gracious N, Nair RR. Pharmacogenetics Based Dose Prediction Model for Initial Tacrolimus Dosing in Renal Transplant Recipients. Front Pharmacol. 2021 Nov 30;12:726784. doi: 10.3389/fphar.2021.726784. PMID: 34916931; PMCID: PMC8669916.
• Thomas JM, Sasankan D, Surendran S, Abraham M, Rajavelu A, Kartha CC. Aberrant regulation of retinoic acid signaling genes in cerebral arterio venous malformation nidus and neighboring astrocytes. J Neuroinflammation. 2021 Mar 1;18(1):61. doi: 10.1186/s12974-021-02094-2. PMID: 33648532; PMCID: PMC7923665.
• Mehrotra T, Devi TB, Kumar S, Talukdar D, Karmakar SP, Kothidar A, Verma J, Kumari S, Alexander SM, Retnakumar RJ, Devadas K, Ray A, Mutreja A, Nair GB, Chattopadhyay S, Das B. Antimicrobial resistance and virulence in Helicobacter pylori: Genomic insights. Genomics. 2021 Nov;113(6):3951-3966. doi: 10.1016/j.ygeno.2021.10.002. Epub 2021 Oct 5. PMID: 34619341.
• Krishna AP, John S, Shinde PL, Mishra R. Proteo-transcriptomics meta-analysis identifies SUMO2 as a promising target in glioblastoma multiforme therapeutics. Cancer Cell Int. 2021 Oct 29;21(1):575. doi: 10.1186/s12935-021-02279-y. PMID: 34715855; PMCID: PMC8555349.
• Devi TB, Devadas K, George M, Gandhimathi A, Chouhan D, Retnakumar RJ, Alexander SM, Varghese J, Dharmaseelan S, Chandrika SK, Jissa VT, Das B, Nair GB, Chattopadhyay S. Low Bifidobacterium Abundance in the Lower Gut Microbiota Is Associated With Helicobacter pylori-Related Gastric Ulcer and Gastric Cancer. Front Microbiol. 2021 Feb 26;12:631140. doi: 10.3389/fmicb.2021.631140. PMID: 33717022; PMCID: PMC7953064.
• Alexander SM, Retnakumar RJ, Chouhan D, Devi TNB, Dharmaseelan S, Devadas K, Thapa N, Tamang JP, Lamtha SC, Chattopadhyay S. Helicobacter pylori in Human Stomach: The Inconsistencies in Clinical Outcomes and the Probable Causes. Front Microbiol. 2021 Aug 17;12:713955. doi: 10.3389/fmicb.2021.713955. PMID: 34484153; PMCID: PMC8416104.
• Mohan A, Raj Rajan R, Mohan G, Kollenchery Puthenveettil P, Maliekal TT. Markers and Reporters to Reveal the Hierarchy in Heterogeneous Cancer Stem Cells. Front Cell Dev Biol. 2021 Jun 3;9:668851. doi: 10.3389/fcell.2021.668851. PMID: 34150761; PMCID: PMC8209516.
• Remya C, Dileep KV, Variyar EJ, Zhang KYJ, Omkumar RV, Sadasivan C. Chemical similarity assisted search for acetylcholinesterase inhibitors: Molecular modeling and evaluation of their neuroprotective properties. Int J Biol Macromol. 2021 Mar 31;174:466-476. doi: 10.1016/j.ijbiomac.2021.01.148. Epub 2021 Jan 23. PMID: 33497692.
• Avni D, Harikumar KB, Sanyal AJ, Spiegel S. Deletion or inhibition of SphK1 mitigates fulminant hepatic failure by suppressing TNFα-dependent inflammation and apoptosis. FASEB J. 2021 Mar;35(3):e21415. doi: 10.1096/fj.202002540R. PMID: 33566377; PMCID: PMC8491138.
• Kalathil D, John S, Nair AS. FOXM1 and Cancer: Faulty Cellular Signaling Derails Homeostasis. Front Oncol. 2021 Feb 15;10:626836. doi: 10.3389/fonc.2020.626836. PMID: 33680951; PMCID: PMC7927600.
• Mohan A, Raj R R, Mohan G, K P P, Thomas Maliekal T. Reporters of Cancer Stem Cells as a Tool for Drug Discovery. Front Oncol. 2021 Apr 22;11:669250. doi: 10.3389/fonc.2021.669250. PMID: 33968778; PMCID: PMC8100607.
• Varghese PC, Rajam SM, Nandy D, Jory A, Mukherjee A, Dutta D. Histone chaperone APLF level dictates the implantation of mouse embryos. J Cell Sci. 2021 Jan 13;134(1):jcs246900. doi: 10.1242/jcs.246900. PMID: 33277378.
• Chandel S, Manikandan A, Mehta N, Nathan AA, Tiwari RK, Mohapatra SB, Chandran M, Jaleel A, Manoj N, Dixit M. The protein tyrosine phosphatase PTP-PEST mediates hypoxia-induced endothelial autophagy and angiogenesis via AMPK activation. J Cell Sci. 2021 Jan 11;134(1):jcs250274. doi: 10.1242/jcs.250274. PMID: 33323505.
• Verma A, Sumi S, Seervi M. Heat shock proteins-driven stress granule dynamics: yet another avenue for cell survival. Apoptosis. 2021 Aug;26(7-8):371-384. doi: 10.1007/s10495-021-01678-w. Epub 2021 May 12. PMID: 33978921.
• Kalimuthu K, Keerthana CK, Mohan M, Arivalagan J, Christyraj JRSS, Firer MA, Choudry MHA, Anto RJ, Lee YJ. The emerging role of selenium metabolic pathways in cancer: New therapeutic targets for cancer. J Cell Biochem. 2021 Dec 21. doi: 10.1002/jcb.30196. Epub ahead of print. PMID: 34935169.
• Nayar S. Exploring the Role of a Cytokinin-Activating Enzyme LONELY GUY in Unicellular Microalga Chlorella variabilis. Front Plant Sci. 2021 Jan 29;11:611871. doi: 10.3389/fpls.2020.611871. PMID: 33613586; PMCID: PMC7891180.
• George B, Amjesh R, Paul AM, Santhoshkumar TR, Pillai MR, Kumar R. Evidence of a dysregulated vitamin D endocrine system in SARS-CoV-2 infected patient's lung cells. Sci Rep. 2021 Apr 21;11(1):8570. doi: 10.1038/s41598-021-87703-z. PMID: 33883570; PMCID: PMC8060306.
• George B, Pillai PM, Paul AM, Amjesh R, Leitzel K, Ali SM, Sandiford O, Lipton A, Rameshwar P, Hortobagyi GN, Pillai MR, Kumar R. Cellular Fitness Phenotypes of Cancer Target Genes from Oncobiology to Cancer Therapeutics. Cells. 2021 Feb 18;10(2):433. doi: 10.3390/cells10020433. PMID: 33670680; PMCID: PMC7921985.
• Madhavan A, Arun KB, Pushparajan AR, Balaji M, Kumar RA. Transcription Repressor Protein ZBTB25 Associates with HDAC1-Sin3a Complex in Mycobacterium tuberculosis-Infected Macrophages, and Its Inhibition Clears Pathogen by Autophagy. mSphere. 2021 Feb 24;6(1):e00036-21. doi: 10.1128/mSphere.00036-21. PMID: 33627504; PMCID: PMC8544881.
• Senapati P, Bhattacharya A, Das S, Dey S, Sudarshan D, G S, Vishwakarma J, Sudevan S, Ramachandran R, Maliekal TT, Kundu TK. Histone chaperone Nucleophosmin regulates transcription of key genes involved in oral tumorigenesis. Mol Cell Biol. 2021 Dec 13:MCB0066920. doi: 10.1128/MCB.00669-20. Epub ahead of print. PMID: 34898280.
• Jabeena CA, Govindaraju G, Rawat M, Gopi S, Sethumadhavan DV, Jaleel A, Sasankan D, Karmodiya K, Rajavelu A. Dynamic association of the H3K64 trimethylation mark with genes encoding exported proteins in Plasmodium falciparum. J Biol Chem. 2021 Jan-Jun;296:100614. doi: 10.1016/j.jbc.2021.100614. Epub 2021 Apr 9. PMID: 33839154; PMCID: PMC8095176.
• Issac J, Raveendran PS, Das AV. RFX1: a promising therapeutic arsenal against cancer. Cancer Cell Int. 2021 May 8;21(1):253. doi: 10.1186/s12935-021-01952-6. PMID: 33964962; PMCID: PMC8106159.
• Kunnummal M, Angelin M, Das AV. PIWI proteins and piRNAs in cervical cancer: a propitious dart in cancer stem cell-targeted therapy. Hum Cell. 2021 Nov;34(6):1629-1641. doi: 10.1007/s13577-021-00590-4. Epub 2021 Aug 9. PMID: 34374035.
• Khan MIK, Charles RCM, Ramachandran R, Gupta S, Govindaraju G, Mishra R, Rajavelu A, Coumar MS, Chavali S, Dhayalan A. The ribosomal protein eL21 interacts with the protein lysine methyltransferase SMYD2 and regulates its steady state levels. Biochim Biophys Acta Mol Cell Res. 2021 Aug;1868(9):119079. doi: 10.1016/j.bbamcr.2021.119079. Epub 2021 Jun 17. PMID: 34147559.
• Aneesh Kumar A, Ajith Kumar GS, Satheesh G, Surendran A, Chandran M, Kartha CC, Jaleel A. Proteomics Analysis Reveals Diverse Molecular Characteristics between Endocardial and Aortic-Valvular Endothelium. Genes (Basel). 2021 Jun 30;12(7):1005. doi: 10.3390/genes12071005. PMID: 34208790; PMCID: PMC8304717.
• James S, Aparna JS, Babu A, Paul AM, Lankadasari MB, Athira SR, Kumar SS, Vijayan Y, Namitha NN, Mohammed S, Reshmi G, Harikumar KB. Cardamonin Attenuates Experimental Colitis and Associated Colorectal Cancer. Biomolecules. 2021 Apr 29;11(5):661. doi: 10.3390/biom11050661. PMID: 33947113; PMCID: PMC8146383.
• Verma M, Khan MIK, Kadumuri RV, Chakrapani B, Awasthi S, Mahesh A, Govindaraju G, Chavali PL, Rajavelu A, Chavali S, Dhayalan A. PRMT3 interacts with ALDH1A1 and regulates gene-expression by inhibiting retinoic acid signaling. Commun Biol. 2021 Jan 25;4(1):109. doi: 10.1038/s42003-020-01644-3. PMID: 33495566; PMCID: PMC7835222.
• Gopinath D, Menon RK, Wie CC, Banerjee M, Panda S, Mandal D, Behera PK, Roychoudhury S, Kheur S, Botelho MG, Johnson NW. Differences in the bacteriome of swab, saliva, and tissue biopsies in oral cancer. Sci Rep. 2021 Jan 13;11(1):1181. doi: 10.1038/s41598-020-80859-0. PMID: 33441939; PMCID: PMC7806708.
• Lee SH, Kim EH, O'neal JT, Dale G, Holthausen DJ, Bowen JR, Quicke KM, Skountzou I, Gopal S, George S, Wrammert J, Suthar MS, Jacob J. The amphibian peptide Yodha is virucidal for Zika and dengue viruses. Sci Rep. 2021 Jan 12;11(1):602. doi: 10.1038/s41598-020-80596-4. PMID: 33436917; PMCID: PMC7804942.
• Prakash A, Banerjee M. Genomic selection signatures in autism spectrum disorder identifies cognitive genomic tradeoff and its relevance in paradoxical phenotypes of deficits versus potentialities. Sci Rep. 2021 May 13;11(1):10245. doi: 10.1038/s41598-021-89798-w. PMID: 33986442; PMCID: PMC8119484.
• Asok Kumar N, Muraleedharan Suma S, Kunnakkadan U, Nag J, Koolaparambil Mukesh R, Lyles DS, Johnson JB. Functional Dissection of the Dominant Role of CD55 in Protecting Vesicular Stomatitis Virus against Complement-Mediated Neutralization. Viruses. 2021 Feb 26;13(3):373. doi: 10.3390/v13030373. PMID: 33652918; PMCID: PMC7996768.
• Sreeja JS, Jyothy A, Sengupta S. α-Fodrin in Cytoskeletal Organization and the Activity of Certain Key Microtubule Kinesins. Genes (Basel). 2021 May 17;12(5):750. doi: 10.3390/genes12050750. PMID: 34067543; PMCID: PMC8156673.
• Prasad SR, Kumar TSS, Jayakrishnan A. Nanocarrier-based drug delivery systems for bone cancer therapy: a review. Biomed Mater. 2021 May 14;16(4). doi: 10.1088/1748-605X/abf7d5. PMID: 33853043.
• Sudhir BJ, Keelara AG, Venkat EH, Kazumata K, Sundararaman A. The mechanobiological theory: a unifying hypothesis on the pathogenesis of moyamoya disease based on a systematic review. Neurosurg Focus. 2021 Sep;51(3):E6. doi: 10.3171/2021.6.FOCUS21281. PMID: 34469862.
• Richard V, Kumar TRS, Pillai RM. Transitional dynamics of cancer stem cells in invasion and metastasis. Transl Oncol. 2021 Jan;14(1):100909. doi: 10.1016/j.tranon.2020.100909. Epub 2020 Oct 10. PMID: 33049522; PMCID: PMC7557893.
• Sethumadhavan DV, Govindaraju G, Jabeena CA, Rajavelu A. Plasmodium falciparum SET2 domain is allosterically regulated by its PHD-like domain to methylate at H3K36. Biochim Biophys Acta Gene Regul Mech. 2021 Oct;1864(10):194744. doi: 10.1016/j.bbagrm.2021.194744. Epub 2021 Aug 11. PMID: 34389510.
• Hansen JP, Ali WM, Sivadasan R, Rajeeve K. Bacteria-Cancer Interface: Awaiting the Perfect Storm. Pathogens. 2021 Oct 14;10(10):1321. doi: 10.3390/pathogens10101321. PMID: 34684270; PMCID: PMC8540461.
• Garg SG, Kapust N, Lin W, Knopp M, Tria FDK, Nelson-Sathi S, Gould SB, Fan L, Zhu R, Zhang C, Martin WF. Anomalous Phylogenetic Behavior of Ribosomal Proteins in Metagenome-Assembled Asgard Archaea. Genome Biol Evol. 2021 Jan 7;13(1):evaa238. doi: 10.1093/gbe/evaa238. PMID: 33462601; PMCID: PMC7813640.
• Abdul F, Sreenivas N, Kommu JVS, Banerjee M, Berk M, Maes M, Leboyer M, Debnath M. Disruption of circadian rhythm and risk of autism spectrum disorder: role of immune-inflammatory, oxidative stress, metabolic and neurotransmitter pathways. Rev Neurosci. 2021 May 27. doi: 10.1515/revneuro-2021-0022. Epub ahead of print. PMID: 34047147.
• Mudaliar P, Pradeep P, Abraham R, Sreekumar E. Targeting cap-dependent translation to inhibit Chikungunya virus replication: selectivity of p38 MAPK inhibitors to virus-infected cells due to autophagy-mediated down regulation of phospho-ERK. J Gen Virol. 2021 Jul;102(7). doi: 10.1099/jgv.0.001629. PMID: 34328830.
• Girija A, Vijayanathan M, Sreekumar S, Basheer J, Menon TG, Krishnankutty RE, Soniya EV. Harnessing the natural pool of polyketide and non-ribosomal peptide family: A route map towards novel drug development. Curr Mol Pharmacol. 2021 Mar 19. doi: 10.2174/1874467214666210319145816. Epub ahead of print. PMID: 33745440.
• Geetha RG, Krishnankutty Nair Chandrika S, Saraswathy GG, Nair Sivakumari A, Sakuntala M. ROS Dependent Antifungal and Anticancer Modulations of Piper colubrinum Osmotin. Molecules. 2021 Apr 13;26(8):2239. doi: 10.3390/molecules26082239. PMID: 33924432; PMCID: PMC8070354.
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• Philip S, Tom G, Balakrishnan Nair P, Sundaram S, Velikkakathu Vasumathy A. Tinospora cordifolia chloroform extract inhibits LPS-induced inflammation via NF-κB inactivation in THP-1cells and improves survival in sepsis. BMC Complement Med Ther. 2021 Mar 20;21(1):97. doi: 10.1186/s12906-021-03244-y. PMID: 33743681; PMCID: PMC7980548.
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• Meparambu Prabhakaran D, Patel HR, Sivakumar Krishnankutty Chandrika S, Thomas S. Genomic attributes differ between Vibrio parahaemolyticus environmental and clinical isolates including pathotypes. Environ Microbiol Rep. 2021 Aug 30. doi: 10.1111/1758-2229.13000. Epub ahead of print. PMID: 34461673.
• Suryaletha K, Chandrika SK, Thomas S. Comprehensive genomics depict accessory genes encoding pathogenicity and biofilm determinants in Enterococcus faecalis. Future Microbiol. 2021 Feb;16(3):175-184. doi: 10.2217/fmb-2020-0111. Epub 2021 Feb 2. PMID: 33528277.
• Kumar AA, Anusree VR, Satheesh G, Vijayakumar G, Chandran M, Simon L, Lakshmi S, Pillai MR, Jaleel A. Hyperhomocysteinemia-related serum metabolome alterations not normalized by short-term folic acid treatment. Metabolomics. 2021 May 9;17(5):47. doi: 10.1007/s11306-021-01798-z. PMID: 33966131.
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Book Chapter

• Kozhinjampara R Mahendran. Building Synthetic Transmembrane Peptide Pores. Methods Mol Biol 2021;2186:19-32. doi: 10.1007/978-1-0716-0806-7_3. Book Series There are 2267 volumes in this series Published 1984 - 2021
• Haritha H. Nair, Vijai V. Alex and Ruby John. 14-Significance of nutraceuticals in cancer therapy. In: Evolutionary Diversity as a Source for Anticancer Molecules, Academic Press, 2021,Pages 309-321,ISBN 9780128217108.
• Aanthalakshmy Sundararaman, Manipa Saha, Saurav Kumar and Annapoorni Rangarajan. Anoikis: Extracellular Matrix regulation of life and death. Chapter: Metabolic regulation of Anoikis Springer Publishing
• R. Dhanya. Role of citrus flavonoids in the management of diabetes and its complications.Recent Advancements and Research in Biological Sciences (ISBN: 978-81-952529-1-6). (Volume 1, Edition-1, May- 2021).