Rajiv Gandhi Centre for Biotechnology (RGCB), Department of Biotechnology, Government of India

Cryo-EM structure provides insights into the unusual heptameric assembly of rice (Oryza sativa L.) ClpB1 AAA+ ATPase

Chacko Jobichen*^,#, Ketul Saharan*, Archana Samal, Yeu Khai Choong, Manas Kumar Jagdev, Chinmayee Mohapatra, Shi Jian, Richa Babbar, Renwick C.J. Dobson, Anil Grover, Dileep Vasudevan^#, J. Sivaraman^# (2025)

International Journal of Biological Macromolecules 10.1016/j.ijbiomac.2025.143917
(^*Co-first authors; ^#Co-corresponding authors)

2.0 Å cryo-EM structure of the 55 kDa nucleoplasmin domain of AtFKBP53

Nikhil Bharambe^*, Ketul Saharan^*, Dileep Vasudevan^#, Sandip Basak^# (2025)

Journal of Structural Biology doi.org/10.1016/j.jsb.2025.108203
(^*Co-first authors; ^#Co-corresponding authors)

Structure-function studies of a nucleoplasmin isoform from Plasmodium falciparum

Ketul Saharan, Somanath Baral, Surajit Gandhi, Ajit Kumar Singh, Sourav Ghosh, Rahul Das, Viswanathan Arun Nagaraj, Dileep Vasudevan (2025)

Journal of Biological Chemistry doi.org/10.1016/j.jbc.2025.108379

Characterization of the Arabidopsis thaliana chromatin remodeler DEK3 for its interaction with histones and DNA.

Rajivgandhi Sundaram, Surajit Gandhi, Claudia Jonak, Dileep Vasudevan (2024)

Biochimie doi: 10.1016/j.biochi.2024.07.018

Structure-function analyses reveal Arabidopsis thaliana HDA7 to be an inactive histone deacetylase

Ketul Saharan,Somanath Baral,Nausad Hossain Shaikh,Dileep Vasudevan (2024)

Current Research in Structural Biology doi.org/10.1016/j.crstbi.2024.100136

Crystal structure of the N-terminal domain of MtClpC1 in complex with the anti-mycobacterial natural peptide Lassomycin.

Manas K. Jagdev, Dharma R. Tompa, Losee L. Ling, Aaron J. Peoples, Jagneshwar Dandapat, Chinmayee Mohapatra, Kim Lewis, Dileep Vasudevan(2023)

International Journal of Biological Macromolecules 253(2): 126771. doi: 10.1016/j.ijbiomac.2023.126771.

Editorial: Chromatin structure and function.

Laxmi N. Mishra, Christophe Thiriet, Dileep Vasudevan. (2023)

Frontiers in Genetics 14: 1140534. doi: 10.3389/fgene.2023.1140534

Plant-specific HDT family histone deacetylases are nucleoplasmins

Ruchir C. Bobde, Ashish Kumar, Dileep Vasudevan. (2022)

The Plant Cell 34(12): 4760-4777. doi: 10.1093/plcell/koac275

The plant nucleoplasmin AtFKBP43 needs its extended arms for histone interaction.

Ajit K. Singh, Ketul Saharan, Somanath Baral, Dileep Vasudevan. (2022)

BBA - Gene Regulatory Mechanisms 1865(7): 194872. doi: 10.1016/j.bbagrm.2022.194872

Structural insights into proteins from White spot syndrome virus: perspectives on structure-based anti-viral strategies.

Aritreyee Datta, Shaikh N. Hossain, Chinmayee Mohapatra, Dileep Vasudevan. (2022)

Reviews in Aquaculture 14(4): 1745-1756. doi: 10.1111/raq.12670

Crystal packing reveals rapamycin-mediated homodimerization of an FK506-binding domain.

Ajit K. Singh, Ketul Saharan, Somanath Baral, Sheng Luan, Dileep Vasudevan. (2022)

International Journal of Biological Macromolecules 206: 670-680. doi: 10.1016/j.ijbiomac.2022.02.107.

In vitro characterization of histone chaperones using analytical, pull-down and chaperoning assays.

Ruchir C. Bobde, Ketul Saharan, Somanath Baral, Surajit Gandhi, Archana Samal, Rajivgandhi Sundaram, Ashish Kumar, Ajit K. Singh, Aritreyee Datta, Dileep Vasudevan. (2021)

Journal of Visualized Experiments [JoVE] 63218. doi: 10.3791/63218.

Interdomain connecting loop and J loop structures determine cross-species compatibility of PCNA.

Premlata Kumari, Rajivgandhi Sundaram, Kodavati Manohar, Dileep Vasudevan#, Narottam Acharya (2021)
[# Co-corresponding authors]

Journal of Biological Chemistry 297(1): 100911. doi: 10.1016/j.jbc.2021.100911.

Structural analyses of PCNA from the fungal pathogen Candida albicans identify three regions with species-specific conformations.

Rajivgandhi Sundaram, Kodavati Manohar, Shraddheya K. Patel, Narottam Acharya, Dileep Vasudevan. (2021)

FEBS Letters 595(9): 1328-1349. doi: 10.1002/1873-3468.14055.

Structural basis of nucleosome recognition and modulation.

Rajivgandhi Sundaram, Dileep Vasudevan. (2020)

BioEssays 42(9): 1900234. doi: 10.1002/bies.201900234.

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Dileep Vasudevan, PhD

Scientist F

Selected Publications