Selected Publications
Luminal epithelial cells integrate variable responses to aging into stereotypical changes that underlie breast cancer susceptibility.
Rosalyn W Sayaman, Masaru Miyano, Eric G Carlson, Parijat Senapati, Arrianna Zirbes, Sundus F Shalabi, Michael E Todhunter, Victoria E Seewaldt, Susan L Neuhausen, Martha R Stampfer, Dustin E Schones, Mark A LaBarge (2024)
eLife doi: 10.7554/eLife.95720.
Loss of epigenetic suppression of retrotransposons with oncogenic potential in aging mammary luminal epithelial cells.
Parijat Senapati, Masaru Miyano, Rosalyn W. Sayaman, Mudaser Basam, Amy Leung, Mark A. LaBarge, Dustin E. Schones (2023)
Genome Research doi: 10.1101/gr.277511.122
Glucose-regulated O-GlcNAcylation of DNMT1 inhibits DNA methyltransferase activity and maintenance of genomic methylation
Heon Shin, Amy Leung, Kevin R Costello, Parijat Senapati, Hiroyuki Kato, Roger E Moore, Michael Lee, Dimitri Lin, Xiaofang Tang, Patrick Pirrotte, Zhen Bouman Chen, Dustin E Schones (2023)
eLife doi: 10.7554/eLife.85595.
Epigenetic dosage identifies two major and functionally distinct β cell subtypes.
Erez Dror, Luca Fagnocchi, Vanessa Wegert, Stefanos Apostle, Brooke Grimaldi, Tim Gruber, Ilaria Panzeri, Steffen Heyne, Kira Daniela Höffler, Victor Kreiner, Reagan Ching, Tess Tsai-Hsiu Lu, Ayush Semwal, Ben Johnson, Parijat Senapati, Adelheid Lempradl, Dustin Schones, Axel Imhof, Hui Shen, John Andrew Pospisilik (2023)
Cell Metabolism doi: 10.1016/j.cmet.2023.03.008
Histone chaperone Nucleophosmin regulates transcription of key genes involved in oral tumorigenesis.
Parijat Senapati, Aditya Bhattacharya, Sadhan Das, Suchismita Dey, Deepthi Sudarshan, Shyla G, Jyoti Vishwakarma, Surabhi Sudevan, Ravishankar Ramachandran, Tessy Thomas Maliekal, Tapas K Kundu (2022)
Molecular and Cellular Biology doi: 10.1128/MCB.00669-20
Breast-specific molecular clocks comprised of ELF5 expression and promoter methylation identify individuals susceptible to cancer initiation.
Masaru Miyano, Rosalyn W Sayaman, Sundus F Shalabi, Parijat Senapati, Jennifer C Lopez, Brittany Lynn Angarola, Stefan Hinz, Arrianna Zirbes, Olga Anczukow, Lisa D Yee, Mina S Sedrak, Martha R Stampfer, Victoria L Seewaldt, Mark A LaBarge (2021)
Cancer Prevention Research doi: 10.1158/1940-6207.CAPR-20-0635
Dietary glutamine supplementation suppresses epigenetically-activated oncogenic pathways to inhibit melanoma tumour growth.
Mari B Ishak Gabra, Ying Yang, Haiqing Li, Parijat Senapati, Eric A Hanse, Xazmin H Lowman, Thai Q Tran, Lishi Zhang, Linda T Doan, Xiangdong Xu, Dustin E Schones, David A Fruman, Mei Kong (2020)
Nature Communications doi: 10.1038/s41467-020-17181-w
Hyperinsulinemia promotes aberrant histone acetylation in triple-negative breast cancer.
Parijat Senapati, Hiroyuki Kato, Michael Lee, Amy Leung, Christine Thai, Angelica Sanchez, Emily J Gallagher, Derek LeRoith, Victoria L Seewaldt, David K Ann, Dustin E Schones (2019)
Epigenetics & Chromatin doi: 10.1186/s13072-019-0290-9
A novel Angiotensin II induced long noncoding RNA Giver regulates oxidative stress, inflammation, and proliferation in vascular smooth muscle cells.
Sadhan Das, Erli Zhang, Parijat Senapati, Vishnu Amaram, Marpadga A Reddy, Kenneth Stapleton, Amy Leung, Linda Lanting, Mei Wang, Zhuo Chen, Mitsuo Kato, Hyung Jung Oh, Qianyun Guo, Xinyue Zhang, Bin Zhang, Haitong Zhang, Qinghao Zhao, Wei Wang, Yongjian Wu, Rama Natarajan (2018)
Circulation Research doi: 10.1161/CIRCRESAHA.118.313207
Diabetes Mellitus-induced Long Noncoding RNA Dnm3os regulates macrophage functions and inflammation via nuclear mechanisms.
Sadhan Das, Marpadga A Reddy, Parijat Senapati, Kenneth Stapleton, Linda Lanting, Mei Wang, Vishnu Amaram, Rituparna Ganguly, Lingxiao Zhang, Sridevi Devaraj, Dustin E Schones, Rama Natarajan (2018)
Arteriosclerosis, Thrombosis and Vascular Biology doi: 10.1161/ATVBAHA.117.310663
Regulation of Angiotensin II Actions by Enhancers and Super-enhancers in Vascular Smooth Muscle Cells.
Sadhan Das, Parijat Senapati, Zhuo Chen, Marpadga A Reddy, Rituparna Ganguly, Linda Lanting, Varun Mandi, Anita Bansal, Amy Leung, Selena Zhang, Ye Jia, Xiwei Wu, Dustin E Schones, Rama Natarajan (2017)
Nature Communications doi: 10.1038/s41467-017-01629-7