Loss of epigenetic suppression of retrotransposons with oncogenic potential in aging mammary luminal epithelial cells.

Parijat Senapati, Masaru Miyano, Rosalyn W. Sayaman, Mudaser Basam, Amy Leung, Mark A. LaBarge, Dustin E. Schones (2023)
Genome Research     doi: 10.1101/gr.277511.122

Glucose-regulated O-GlcNAcylation of DNMT1 inhibits DNA methyltransferase activity and maintenance of genomic methylation

Heon Shin, Amy Leung, Kevin R Costello, Parijat Senapati, Hiroyuki Kato, Roger E Moore, Michael Lee, Dimitri Lin, Xiaofang Tang, Patrick Pirrotte, Zhen Bouman Chen, Dustin E Schones (2023)
eLife     doi: 10.7554/eLife.85595.

Epigenetic dosage identifies two major and functionally distinct β cell subtypes.

Erez Dror, Luca Fagnocchi, Vanessa Wegert, Stefanos Apostle, Brooke Grimaldi, Tim Gruber, Ilaria Panzeri, Steffen Heyne, Kira Daniela Höffler, Victor Kreiner, Reagan Ching, Tess Tsai-Hsiu Lu, Ayush Semwal, Ben Johnson, Parijat Senapati, Adelheid Lempradl, Dustin Schones, Axel Imhof, Hui Shen, John Andrew Pospisilik (2023)
Cell Metabolism     doi: 10.1016/j.cmet.2023.03.008

Histone chaperone Nucleophosmin regulates transcription of key genes involved in oral tumorigenesis.

Parijat Senapati, Aditya Bhattacharya, Sadhan Das, Suchismita Dey, Deepthi Sudarshan, Shyla G, Jyoti Vishwakarma, Surabhi Sudevan, Ravishankar Ramachandran, Tessy Thomas Maliekal, Tapas K Kundu (2022)
Molecular and Cellular Biology     doi: 10.1128/MCB.00669-20

Breast-specific molecular clocks comprised of ELF5 expression and promoter methylation identify individuals susceptible to cancer initiation.

Masaru Miyano, Rosalyn W Sayaman, Sundus F Shalabi, Parijat Senapati, Jennifer C Lopez, Brittany Lynn Angarola, Stefan Hinz, Arrianna Zirbes, Olga Anczukow, Lisa D Yee, Mina S Sedrak, Martha R Stampfer, Victoria L Seewaldt, Mark A LaBarge (2021)
Cancer Prevention Research     doi: 10.1158/1940-6207.CAPR-20-0635

Dietary glutamine supplementation suppresses epigenetically-activated oncogenic pathways to inhibit melanoma tumour growth.

Mari B Ishak Gabra, Ying Yang, Haiqing Li, Parijat Senapati, Eric A Hanse, Xazmin H Lowman, Thai Q Tran, Lishi Zhang, Linda T Doan, Xiangdong Xu, Dustin E Schones, David A Fruman, Mei Kong (2020)
Nature Communications     doi: 10.1038/s41467-020-17181-w

Hyperinsulinemia promotes aberrant histone acetylation in triple-negative breast cancer.

Parijat Senapati, Hiroyuki Kato, Michael Lee, Amy Leung, Christine Thai, Angelica Sanchez, Emily J Gallagher, Derek LeRoith, Victoria L Seewaldt, David K Ann, Dustin E Schones (2019)
Epigenetics & Chromatin     doi: 10.1186/s13072-019-0290-9

A novel Angiotensin II induced long noncoding RNA Giver regulates oxidative stress, inflammation, and proliferation in vascular smooth muscle cells.

Sadhan Das, Erli Zhang, Parijat Senapati, Vishnu Amaram, Marpadga A Reddy, Kenneth Stapleton, Amy Leung, Linda Lanting, Mei Wang, Zhuo Chen, Mitsuo Kato, Hyung Jung Oh, Qianyun Guo, Xinyue Zhang, Bin Zhang, Haitong Zhang, Qinghao Zhao, Wei Wang, Yongjian Wu, Rama Natarajan (2018)
Circulation Research     doi: 10.1161/CIRCRESAHA.118.313207

Diabetes Mellitus-induced Long Noncoding RNA Dnm3os regulates macrophage functions and inflammation via nuclear mechanisms.

Sadhan Das, Marpadga A Reddy, Parijat Senapati, Kenneth Stapleton, Linda Lanting, Mei Wang, Vishnu Amaram, Rituparna Ganguly, Lingxiao Zhang, Sridevi Devaraj, Dustin E Schones, Rama Natarajan (2018)
Arteriosclerosis, Thrombosis and Vascular Biology     doi: 10.1161/ATVBAHA.117.310663

Regulation of Angiotensin II Actions by Enhancers and Super-enhancers in Vascular Smooth Muscle Cells.

Sadhan Das, Parijat Senapati, Zhuo Chen, Marpadga A Reddy, Rituparna Ganguly, Linda Lanting, Varun Mandi, Anita Bansal, Amy Leung, Selena Zhang, Ye Jia, Xiwei Wu, Dustin E Schones, Rama Natarajan (2017)
Nature Communications     doi: 10.1038/s41467-017-01629-7

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