Yoga is a complementary healthcare approach with mounting popularity due to its broad psychophysiological health benefits and excellent safety profile. It is a form of mind body medicine typically combining physical postures, breathing techniques, meditation and relaxation response. Previous studies have indicated its benefits for primary and secondary prevention of cardiovascular diseases. However, there is paucity of scientific and experimental data on the molecular mechanism underlying the projected cardiovascular health benefits. In this context, the aim of the present study is to evaluate if yogic practices influence pro-inflammatory status of the heart by decreasing oxidative stress and chronic inflammation.
Jayalekshmi V S
Hyperlipidemia and atherosclerosis.
Role of cyclophilin A on efferocytosis of apoptotic cells and its association with atherosclerosis.
Thushara Thulaseedharan L
Does Cyclophilin A, an immunophilin under high glucose conditions regulate efferocytosis in atherosclerotic lesions?
Nivya. R. M
Validation of small molecule inhibitors designed using in silico method against enzyme Cytochrome Beta 5 Reductase 3 (CYB5R3) that regulate hypertension by NO-induced vasodilation of blood vessels and against another novel enzyme Dopamine Beta Hydroxylase (DBH) which is involved in catecholamine biosynthetic pathway (balancing of which is significant in hypertension regulation). Leads against both CYB5R3 and DBH are screened in Spontaneously Hypertensive Rat (SHR) models to identify antihypertensive efficacy of these novel drugs.
Divya V. S
Does maternal hypercholesterolemia influence cholesterol transport mechanisms across the placenta during gestation?
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