Mechanoresponsive ETS1 causes endothelial dysfunction and arterialization in varicose veins via NOTCH4/DLL4 signaling.

B.J. Sreelakshmi, C.L. Karthika, S. Ahalya, S.R. Kalpana, C.C. Kartha, Sumi S (2024)
European Journal of Cell Biology     Volume 103 Issue 2 doi.org/10.1016/j.ejcb.2024.151420

Oscillatory shear stress modulates Notch-mediated endothelial mesenchymal plasticity in cerebral arteriovenous malformations.

Karthika CL, Vani Venugopal, Sreelakshmi BJ, Krithika S, Jaya Mary Thomas, Mathew Abraham, Kartha CC, Rajavelu A,Sumi S* (2023)
Cellular & Molecular Biology Letters.     2023. 28:22.also DOI 10.1186/s11658-023-00436-x

DNA methylation signatures on vascular differentiation genes are aberrant in vessels of human cerebral arteriovenous malformation nidus.

Thomas JM, Sasankan D, Abraham M, Sumi S, Kartha CC, Rajavelu A ( 2022)
Clinical Epigenetics.     2022 Oct 13; 14(1):127. doi: 10.1186/s13148-022-01346-z.

Shear stress alterations activate BMP4/pSMAD5 signaling and induce endothelial mesenchymal transition in varicose veins.

Karthika CL, Ahalya S, Vyshna Beena, BinilRaj SS, RaviKumar BL, Ravi Kalyani, Radhakrishnan N, Kalpana SR, Kartha CC, Sumi S.(2021)
Cells     2021.10(12), 3563; https://doi.org/10.3390/cells10123563

Molecular Biomarkers and Drug Targets in Brain Arteriovenous and Cavernous Malformations: Where Are We?

Vani Venugopal, S. Sumi (2021)
Stroke     doi.org/10.1161/STROKEAHA.121.035654

Neurovascular inflammation in the pathogenesis of brain arteriovenous malformations.

Krithika S and Sumi S* (2020)
Journal of Cellular Physiology     https://doi.org/10.1002/jcp.30226.

Hemodynamics mediated epigenetic regulators in the pathogenesis of vascular diseases.

Karthika CL#, Ahalya S#, Radhakrishnan N, Kartha CC, Sumi S* (2020)
Molecular and Cellular Biochemistry     https://doi.org/10.1007/s11010-020-03890-9.
* Corresponding author

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