Rajiv Gandhi Centre for Biotechnology (RGCB), Department of Biotechnology, Government of India

Cholesterol regulates insulin-induced mTORC1 signaling.

Kolaparamba V. Navyasree, Shikha T. Ramesh, Perunthottathu K. Umasankar (2023)

Journal of Cell Science doi.org/10.1242/jcs.261402

A rapid bead-based assay for screening of SARS-CoV-2 neutralizing antibodies.

Lupitha SS, Darvin P, Chandrasekharan A, Varadarajan SN, Divakaran SJ, Easwaran S, Nelson-Sathi S, Umasankar PK., Jones S, Joseph I, Pillai MR, Santhoshkumar TR. (2022)

Antib Ther. 5(2):100-110.

Mutational landscape and in silico structure models of SARS-CoV-2 spike receptor binding domain reveal key molecular determinants for virus-host interaction.

Nelson-Sathi S^*, Umasankar PK^*, Sreekumar E, Nair RR, Joseph I, Nori SRC, Philip JS, Prasad R, Navyasree KV, Ramesh S, Pillai H, Ghosh S, Santosh Kumar TR, Pillai MR. (2022)

BMC Molecular and Cell Biology 23(1):2. (*Corresponding author)

FCHO controls AP2's initiating role in endocytosis through a PtdIns(4,5)P2-dependent switch.

Zaccai NR, Kadlecova Z, Dickson VK, Korobchevskaya K, Kamenicky J, Kovtun O, Umasankar PK, Wrobel AG, Kaufman JGG, Gray SR, Qu K, Evans PR, Fritzsche M, Sroubek F, Höning S, Briggs JAG, Kelly BT, Owen DJ, Traub LM. (2022)

Science Advances doi: 10.1126/sciadv.abn2018

BMP2K phosphorylates AP-2 and regulates clathrin-mediated endocytosis.

Shikha T. Ramesh, Kolaparamba V. Navyasree, Sneha Sah, Anjitha B. Ashok, Nishada Qathoon, Suryasikha Mohanty, Rajeeb K. Swain, Perunthottathu K. Umasankar (2021)

Traffic doi.org/10.1111/tra.12814

Allosteric feed-forward activation of AP-2 via FCHO-BMP2K axis promotes clathrin-mediated endocytosis.

Shikha RT, Navyasree KV, Anjitha AB, Qathoon N, Mohanty S, Swain RK, Umasankar PK

bioRxiv doi.org/10.1101/870899

Transient Fcho1/2.Eps15/R.AP-2 Nanoclusters Prime the AP-2 Clathrin Adaptor for Cargo Binding

Ma L*,Umasankar PK*, Wrobel AG*, Lymar A, McCoy AJ, Holkar SS, Jha A, Pradhan-Sundd T, Watkins SC, Owen DJ, Traub LM.(2016)

Developmental Cell. 37(5):428-443. (* Co-first author)

See complete publication list

Umasankar P . K, PhD

DBT-Ramalingaswami Faculty Fellow

Selected Publications