Academic Positions

  • Scientist G

    Rajiv Gandhi Centre for Biotechnology

  • Scientist F

    Rajiv Gandhi Centre for Biotechnology

  • Scientist E-II

    Rajiv Gandhi Centre for Biotechnology

  • Scientist E-I

    Rajiv Gandhi Centre for Biotechnology

  • Visiting Scientist

    Dept. of Bioimmunotherapy, M.D. Anderson Cancer Center, Houston, Texas, USA

  • Research Associate

    Rajiv Gandhi Centre for Biotechnology

Education

  • PhD Biochemistry 1995

    Amala Cancer Research Centre, Thrissur

  • M.Ed Physical Science 1989

    Govt. Training College, Thrissur

  • M.Sc Chemistry 1985

    Govt College, Madappally

Academic Honors

  • Fellow, National Academy of Sciences, Allahabad

  • Fellow, Academy of Sciences, Thiruvananthapuram, India

Awards

  • 2019
    Keystone Symposia Global Health travel award by Bill and Melinda Gates Foundation to attend Keystone Symposia meeting, 'Why So Many Ways to Die? Apoptosis, Necroptosis, Pyroptosis and Beyond', Guarujá, São Paulo, Brazil. November 19-23, 2019
  • 2015
    Excellence award for outstanding performance, RGCB, Promotion assessment committee
  • 2004
    National Woman Bio-Scientist Award, DBT, Govt of India
  • 1995
    Fr. Gabriel Golden Jubilee Award for best paper: Amala Cancer Research Centre, Thrissur

Patents

    Awarded

  • Ruby John Anto, A chemotherapeutic composition used in the treatment of cancer: Filing Number: #1184/Del/2004. IPR- Patent number: 241416, Date of grant-02/07/2010: Funding by DBT, Govt. of India

  • Ruby John Anto and Lakshmi R Nath, Uttroside B and derivatives thereof as therapeutics for hepatocellular carcinoma, funding by Rajiv Gandhi Centre For Biotechnology.
    National Patent Application No. 201641018401 dated 28th May 2016
    International patent Application No. PCT/ IN20 17/050204 dated 27th May 2017
    Current patent Status
    India- Replied to FER on Dec 14,2020 (Application in Amended Examination)

    1. US: WIPO patentscope number US20190160088, November 26,2018, Patent granted.
    2. Canada: WIPO patentscope number 3,026,426, November 28,2018, Patent granted.
    3. Japan: WIPO patentscope number JP2019520425, Patent granted.
    4. South Korea: WIPO patentscope number KR1020190008323, Patent granted.

  • Technology transfer/commercialization

  • Signed an MOU with Oklahoma Medical Research Foundation, USA for the clinical translation of Uttroside B in liver cancer patients on January 31, 2017.

  • Transferred the technology to the multi-national company, Q Biomed. And received the first milestone payment on June 15, 2017.
    (https://adisinsight.springer.com/drugs/800048876);
    https://qbiomed.com/index.php/pipeline/uttroside

  • Received Orphan Drug Designation to Uttroside B on January 27, 2021.
    https://www.prnewswire.com/news-releases/q-biomeds-uttroside-b-receives-us-fda-orphan-drug-designation-in-the-treatment-of-liver-cancer-301215876.html
    https://www.biospace.com/article/releases/q-biomed-s-uttroside-b-receives-u-s-fda-orphan-drug-designation-in-the-treatment-of-liver-cancer/

  • Filed

  • Ruby John Anto and Jayesh Antony, Extracts from a plant, processes for obtaining the extracts and fractions and applications thereof, Filed on: 20.09.2010, Patent Application No. 2743/CHE/2010: Funding by RGCB

  • C Mohandas, Bala Nambisan, Ruby John Anto, Vino T. Cheriyan and S. Nishanth Kumar. Anticancer activity of a cyclic dipeptide isolated from novel bacteria associated with Rhabditis sp., Filed on: 11-03-2011 Patent Application No. 820/CHE/2011). Funding by Indian Council for Agricultural Research

Memberships

  • Member, European Association For Cancer Research

  • Member, American Association of Cancer Research

  • Member, Editorial board - PLOS ONE

  • Member, Editorial Board, Science Letters

  • Member, Editorial board- Asian Journal of Pharmacological Sciences

  • Member, American Society For Biochemistry And Molecular Biology

  • Member, The Biotech Research Society

  • Member, Board of Studies, M.Sc Chemistry, University of Kerala (2004-2007)

  • Member, Board of Studies, MSc Biotechnology, University of Calicut (2007-2010)

Reviewership Editorships

  • Funding Agencies

    • Department of Science and Technology
    • Council of Scientific and Industrial Research
    • Indian Council of Medical Research

  • Journals

    • Antioxid Redox Sign
    • Apoptosis
    • Plos One
    • Int. J. Cancer
    • J. Cellular and Mol. Med.
    • Cell Death &Dis
    • BMC Cancer
    • Immunopharmacol and Immunotoxicol
    • Drug Delivery
    • Evidence Based Complementary &Alternative Med
    • Free Rad Res
    • J.Stem Cells
    • Therapeutic Delivery
    • Int J Pharm
    • Intl J Biochem & Cell Biol

Students Achievements

Contact

Rajiv Gandhi Centre for Biotechnology (RGCB),
Thycaud Post, Poojappura,
Thiruvananthapuram - 695 014, Kerala, India
+91-471-2529400 | 2347975 | 2348753
+91-471-2348096
webmaster@rgcb.res.in

My Gov www.mygov.in Prime Ministers National Relife Fund India Gov www.india.gov.in Make In India www.makeinindia.gov.in Make In India www.iredibleindia.org Data gov in www.data.gov.in www.pib.gov.in

Last Updated on: July 04, 2022
CERT-In Certified Website